At Pfizer, we’re driven to discover the cure—driven to significantly improve the lives of everyone...everywhere. If you’re similarly driven, you’ll find there’s no better place to begin—and continue—your career than at Pfizer.
Science is the foundation of our company. This is why it’s no surprise that our scientists are among the best in the world. We arm them with the resources, technology, and facilities they need to solve some of the world’s most complex health challenges. So, it’s no wonder that the most driven scientists in the world choose to do their life’s passion at Pfizer.
Are you a highly motivated and accomplished Scientist driven to discover the cure?
Our nonclinical research team in Global Investigative Toxicology in Groton, CT is adding to its world class team of leading researchers in Drug Safety.
The primary responsibility of Global Investigative Toxicology is to design and carry out investigative studies to position toxicity findings for molecules in preclinical and clinical development. These efforts include hypothesis-driven mechanistic studies and the development of novel in vitro models. We are seeking a research scientist with expertise in the rapidly evolving areas of 2D and 3D in vitro co-cultures, organoids (such as CNS, liver, kidney or gut), stem cell-derived model systems (iPSC) and/or microphysiological (MPS) models (e.g., fluidics-enabled organ on a chip) to enable the development of more physiologically relevant in vitro assays to improve safety assessment of novel therapeutic molecules.
Reports to a Director of Global Investigative Toxicology
Provides scientific expertise in the areas of 2D and 3D co-cultures, organoid generation and characterization, development and utilization of iPSCs and MPS models
Develops novel in vitro methods that can be used to address toxicity findings/screen subsequent molecules to eliminate toxicity
Generates high quality laboratory-based investigative data to support portfolio progression and/or mechanistic understanding of toxicity findings
Analyzes, documents and reports laboratory data in accordance with company standards and procedures
Effectively communicates experimental findings in both oral and written formats
Functions collaboratively as part of a global multi-disciplinary team
PhD degree in Pharmacology, Toxicology, Molecular Biology, Bioengineering, or a related field; Post-doctoral experience highly desirable
Expertise in applying 3D or MPS models to answer biologically relevant questions in Biology or Toxicology with a strong track record of peer-reviewed publications, scientific presentations (e.g. abstracts, posters, podium presentations) related to 3D, MPS, or iPSC-based science.
Must have prior experience with tissue culture (in particular, primary cultures), iPSC- and MPS-based 3D in vitro models, complex microtissues and organoids
Deep knowledge of standard laboratory assays such as biochemical assays, PCR, western blotting, IHC, flow cytometry, basic high content imaging
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Occasional US business travel and participation in scientific meetings, both national and international
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
Eligible for employee referral bonus
Employer will assist with relocation costs.
Internal Number: 4713346
About Pfizer Inc
Pfizer is one of the world's largest research-based pharmaceuticals firms, producing medicines for ailments in fields including cardiovascular health, metabolism, oncology, and inflammation and immunology
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