Neurodegeneration / Alzheimer’s disease: University of Pittsburgh
University of Pittsburgh School of Public Health is one of the nation’s leading schools of public health, highly ranked among the schools of public health in the USA, with contributions that have influenced public health practice and medical care across the world. Central to its mission is to foster a multidisciplinary research approach to understand and solve health problems.
A postdoctoral fellow position is available in the Iliya Lefterov and Radosveta Koldamova laboratory in the Department of Environmental and Occupational Health at the University of Pittsburgh in Pittsburgh, PA. The successful candidates will become part of a large, multidisciplinary neuroscience and environmental health community focused on neurodegeneration and translational research. The postdoctoral positions in the lab are supported by NIH grants with goals of understanding the role of Apolipoprotein E and other risk factors for late onset Alzheimer’s disease. These projects require integration of multiple techniques for molecular, and genetic analysis of pathological markers. The application of Next Generation Sequencing (NGS) to reveal transcription factor binding genome-wide, histone modifications and expression profiling, including single cell transcriptomes, is a substantial part of the work relevant to all projects. The position requires basic knowledge of statistics and R, experience with bioinformatics tools and software packages necessary to analyze sequencing and MS data. Experience with omix approaches such as proteomics, lipidomics and knowledge of Unix/Mac OS platforms will be considered a plus. The lab utilizes transgenic animals for modeling of Alzheimer’s disease so the applicant should have knowledge on the use of animals as a model system.
The candidates should have creative thinking, excellent communication skills and ability to work collaboratively. Applications should include curriculum vitae and names/contact information of three professional references. For more information/application please contact Radosveta Koldamova or Iliya Lefterov:
The Environmental and Occupational Health (EOH) Department at the University of Pittsburgh has a sound reputation as a leader in training students to Identify agents that affect health, Study the long-term effects of environmental and occupational health risks, and Determine the molecular mechanisms of toxic agents that contribute to the development of certain illnesses and diseases.