The overall goals of our laboratory are to study the development of the blood-brain barrier and the effects of injury on the blood-brain barrier development such as ischemia and inflammation related
injury. We study these effects in fetal sheep and neonatal rodents. The other major area of interest of our laboratory is neuroprotective strategies using anti-cytokine antibodies and a unique patented
neuroprotective agent, inter-alpha inhibitor proteins. The projects involve the large animal and small animal surgery, molecular and immunohistochemical analysis of the neurovascular unit and brain parenchymal cells and uses state-of-the art imaging etc. The candidate will work in a highly-productive scientific environment with the PI, lab technicians, postdoctoral researchers, graduate and undergrad- uate students. Therefore, the candidate will employ innovative approaches to generate high quality data that the candidate is expected to communicate with the research community. The candidate will receive comprehensive mentoring in research and grant writing, has to be highly motivated, enthusi- astic, committed, and have an outstanding work ethic.
Preference will be given to individuals with PhD and/or MD (MS or recent graduate
could be considered) in neuroscience/pharmacology/or related disciplines; expertise with in vivo animal experimentation and hands-on experience with along with neuroscience expertise; familiarity with neuroscience bench work techniques, including molecular biology, immunohistochemistry, cell
culture, antibody, protein production, and proven writing ability. Experience with surgical procedures (large animal and/or Van-nucci neonatal rat models), neurobehavioral, MRI, radioactive materials, data acquisition, and statisti-cal analysis is preferred. The candidate must have excellent
interpersonal, organizational, verbal and written communication skills, and appropriate experience.
Internal Number: 123
About Women & Infants Hospital of RI
Women and Infants Hospital is the premier hospital for women and newborns in Rhode Island. We are affiliated with the Alpert Medical School of Brown University . I am the P.I on four NIH-funded grants; my research is focused on the blood-brain barrier in the rat and ovine fetus.