A position for a postdoctoral fellow is available immediately in the laboratory of Dr. Jennifer K. Lee and Dr. Lee J. Martin (www.jennifer-k-lee-brainresearch.com) in the Department of Anesthesiology and Critical Care Medicine at Johns Hopkins University. Our laboratory examines neuronal and glial cell death, and we have recently identified the proteasome as a potential target for ischemic brain protection. Our NIH-supported research focuses on the cellular and molecular mechanisms of neurodegeneration and white matter injury and pharmacologic/genetic therapeutics in experimental animal and cell culture models of ischemic brain damage and neuronal/oligodendroglial cell death. We investigate proteasome and autophagy function alongside neuroinflammation. The candidate will perform whole animal and cell culture experiments using a combination of physiologic, neuropathologic, cell biology, and molecular approaches, including conditional transient and stable genetic modification of brain, neurons, and oligodendrocytes to interrogate molecular mechanisms of cell injury and therapeutic targets.
Salary will be based on experience and commensurate with NIH guidelines.
Applicants should send a cover letter, CV and the names/contact information for 3 references by email to: firstname.lastname@example.org
The candidate should have a Ph.D. or M.D. with expertise in cell and molecular biology and histopathology and at least one first-author publication in a high-quality peer-reviewed journal. The candidate is expected have proficient and independent research skills. Good oral and written communication skills in English are required. A cooperative team spirit will be valued. High priority candidates need to have, at a minimum, experience with animal surgery, cell culture, and neuropathology, including microscopy (conventional and confocal) and cell counting skills.
Internal Number: 9553640
About Johns Hopkins University
Our NIH-funded laboratory is in the Department of Anesthesiology and Critical Care Medicine at Johns Hopkins University. We study neuronal and glial cell death after ischemic brain injury in animal model and cell culture research.