The Department of Anesthesiology and Perioperative Medicine at the University of Pittsburgh is seeking to fill two postdoctoral research positions in chronic pain and drug dependence. Our NIH-funded research laboratory discovers, visualizes and manipulates pathological changes in CNS circuits that develop in the setting of neuronal injury, inflammation, diabetes, and multiple sclerosis. For example, we discovered new mechanisms by which tissue or nerve injury establishes opposing systems of persistent pain sensitization (latent neuronal sensitization) and analgesia (constitutive activity of Gi-protein coupled receptors) (e.g. Solway et al, PNAS; Corder et al, Science. We also validate new protein and cellular targets for the development of new non-opioid pharmacotherapies and analgesic drugs for chronic pain. Please see our laboratory web pages https://www.taylorlab.anes.pitt.edu/
Within the Pittsburgh Center for Pain Research, we provide a dynamic research environment with exceptional resources for training in basic and translational neuroscience, including scientific mentorship and collaboration within the PCPR, and access to state-of-the-art core facilities at Pitt. Together, we will design experiments that incorporate your existing and emerging strengths in an environment that values hard work, intellectual curiosity, innovative thinking, and teamwork. For more details on training opportunities in pain research such as journal clubs, courses, and seminars, please see our PCPR website http://pcpr.pitt.edu/
Applicants must have a PhD in neuroscience, physiology, pharmacology or equivalent and have demonstrable achievement, interest and preparation to address important questions in neuroscience, including multiple first-authored research articles in well-known international journals. This includes publications with one or more of the following methods: behavioral pharmacology in cre-transgenic mice, in vivo GCaMP calcium imaging / optogenetics / chemogenetics, fluorescence in situ hybridization, single-cell RNA sequencing, or drug vapor self-administration in mice. Current graduate students with US citizenship or permanent residence (green card) in strong training programs are encouraged to apply and will be fully supported in their submission of early-career NIH grants. Advanced fellows with a proven track record of high quality first-author publications in strong journals will also be considered. Please send a Cover Letter that briefly details career goals and prior research experience, CV, and list of three references to Dr. Bradley Taylor via email BKT@pitt.edu
Internal Number: SFN2020March
About UNIVERSITY OF PITTSBURGH
The University of Pittsburgh was ranked third in terms of total NIH funding received in 2018. The Global Livability Index (The Economist) recently ranked Pittsburgh as the second most livable city in America.