Sr Principal Scientist â Hematology & Regeneration NIBR San Diego
Location: San Diego, California
Type: Full Time
Required Education: Doctorate
Internal Number: 106298033
What you'll bring to the role:
* Ph.D. with at least 10 years' experience in experimental hematology or closely related field, with supporting publication record. Experience with HSC biology, molecular biology, and/or immunology is strongly preferred * Demonstrated expertise with Hematopoietic Stem Cell Biology (HSC) biology to establish the in vitro and in vivo models required for establishing drug discovery programs with experience with optimizing gene delivery into HSC or CAR-T biology * The candidate will have a demonstrable record of accomplishment of driving and supporting multiple research projects, and contributions as an author to high-impact, peer-reviewed publications in the field * Leadership experience, including direct reporting and peer-management is required * Will possess excellent oral and written communication skills and an ability to thrive in a dynamic matrix research environment. * Creative problem-solving skills; excellent analytical, communication and organizational skills.
Why consider Novartis?
766 million lives were touched by Novartis medicines in 2021, and while we're proud of this, we know there is so much more we could do to help improve and extend people's lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!
While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers' (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to Eh.firstname.lastname@example.org.
Be part of the next breakthrough! Novartis, a world leader in Gene and Cell Therapies, is looking for a hematology expert to join our team. This position will be in the Novartis Institutes for BioMedical Research (NIBR), the innovation engine of Novartis, focusing on leveraging the breadth of innovation and novel modalities in the development of breakthrough therapies for patients.
NIBR's Regenerative Medicine research group in San Diego California is seeking a highly motivated and collaborative PhD-level Sr. Principal Scientist to build lead a Hematology team dedicated to innovating the next generation of ex vivo engineered therapies as well as moving towards transformative in vivo interventions. The team will focus initially on Sickle Cell Disease and eventually explore aspects of hematopoietic stem cell (HSC) regeneration and HSC-based therapies.
As a leader of a dynamic, multidisciplinary team, you will lead the design and execution of in vitro and in vivo studies enabling the validation and development of innovative cell therapy platforms, genome editing technology, and novel modes of delivery. This exciting role will interface with experts throughout the company in genetic and protein engineering, screening platforms, and translational medicine. The discoveries we make can contribute directly to improving efficacy and accessibility of gene and cell-based therapies to patients.
Your responsibilities include, but are not limited to:
* You will assume a leadership role in the development of novel therapeutic concepts and will contribute at all stages of a project, from inception, validation, candidate selection and through to early clinical development of novel therapies * You will work closely with complementary subject matter experts to develop project strategy, identify key drug discovery issues, propose and implement creative solutions, and guide teams to critical decision points. * Utilization of in vitro and ex vivo cellular manipulations, and in vivo hematological models * Propose and explore new research directions, projects, and/or new technologies. * Self-motivation, ability to work independently, passion for working in an interdisciplinary, collaborative research environment * Manage a team of associates with relevant, diverse expertise
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.